Male Hormone Decline: What You Need to Know After 35
By the mid-30s, many men start noticing subtle changes: energy dips, motivation wanes, workouts feel harder, and recovery takes longer. These shifts aren’t just in your head—they’re rooted in biology. Testosterone and growth hormone (GH), two key hormones for men, naturally decline with age, affecting energy, muscle, and overall vitality. *
Testosterone: The Slow Slide Starts Early
Testosterone doesn’t just vanish overnight—it declines gradually. Research shows total testosterone drops about 0.4–0.8% per year starting in the mid-30s to 40s, while free testosterone declines faster at ~1.3–2% per year due to rising sex hormone–binding globulin (SHBG) [1].
By age 60, roughly 20% of men have clinically low testosterone. By 80, that number approaches 50% [1]. Lower testosterone doesn’t just affect sexual function—it can impact muscle mass, energy levels, mental focus, and even mood. *
Growth Hormone: Your Recovery Hormone Takes a Hit
Growth hormone also declines steadily after the third decade of life, decreasing by approximately 15% every ten years [2]. Daily GH secretion peaks during puberty at about 150 µg/kg/day, then falls to roughly 25 µg/kg/day by age 55 [2].
This drop is linked to multiple factors: reduced slow-wave sleep (when GH pulses occur), changes in hypothalamic and pituitary regulation, and declining IGF-1 levels [2]. The result? More fat mass, less lean muscle, weaker bones, and slower exercise recovery [2]. *
Why This Matters
Hormone decline is natural—but it doesn’t mean you have to accept losing energy, performance, or vitality. * Men over 35 are particularly susceptible because both testosterone and GH are on a downward trend at the same time. The combination can leave you feeling flat, fatigued, and frustrated at the gym. *
The good news: you can support your body with strategies that optimize your lifestyle and enhance your endocrine health. Prioritizing quality sleep, resistance training, balanced nutrition, and recovery can make a noticeable difference. BioPro+® is formulated with clinically studied ingredients designed to support metabolism, energy, and workout recovery—helping men feel sharper, recover faster, and maximize their efforts without prescriptions, needles, or drugs. *
The Bottom Line
Hormone decline after 35 is inevitable, but the effects don’t have to define your life. Understanding the science behind testosterone and GH drops gives you the insight to act. Combine smart lifestyle choices with supportive compounds like those in BioPro+®, and you can maintain energy, lean muscle, and performance longer. *
Take charge now. Back your biology. Back your results.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Works Cited
[1] Cheng, Haoyang et al. “Age-related testosterone decline: mechanisms and intervention strategies.” Reproductive Biology and Endocrinology : RB&E, vol. 22, 1, 144. 14 Nov. 2024. doi:10.1186/s12958-024-01316-5
[2] Garcia JM, Merriam GR, Kargi AY. “Growth Hormone in Aging.” [Updated 2019 Oct 7]. In: Feingold KR, Ahmed SF, Anawalt B, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.