BioPro+ science
The Science of BioPro+®

Not a hormone.
A signal.

BioPro+® is a bio-identical growth factor and peptide formula that provides your body with the same cellular signals it used to produce naturally. 45 studies. One proprietary system. Zero synthetic hormones.

THIS IS WHY BIOPRO+® WORKS
Where It Begins

Nature’s only fully regenerating mammalian organ.

30 studies on cervid antler alone, spanning preclinical, mechanistic, and human research. One of the most extensively studied natural biological tissues.

Antler is one of the only regenerating tissues in mammals on earth, capable of rapid seasonal growth—regenerating up to 25 kilograms of bone mineral in approximately 110 days—and is considered one of the fastest-growing biological tissues studied in mammalian biology.

Velvet antler, harvested before mineralization, contains proteins and peptides studied in pathways associated with growth factors and cellular signaling. As a mammalian tissue, it provides biologically relevant compounds structurally similar to those found in the body, studied for roles in tissue development, recovery, and normal physiological function.

Growth factors are part of the body’s natural communication system, helping coordinate processes such as recovery, energy production, and physiological performance. As the body ages, these signaling processes can become less efficient, contributing to changes in recovery, energy, and overall function. BioPro+® is designed to support the systems these signals regulate—helping maintain how the body recovers, produces energy, and performs across interconnected physiological processes.

The Extraction

BioPro+® Proprietary Extraction Process

Raw velvet antler contains thousands of bioactive compounds. But growth factors are fragile — heat degrades them, oxidation destroys them, and standard processing methods strip the most valuable components before they ever reach a formula.

The result is an extract that is 90% protein by composition, with the growth factor matrix intact and biologically active.
Step 01 Source Selection

Harvested at peak biological activity — the cartilaginous stage before mineralization, when growth factor density is highest.

Step 02 Proprietary Concentration Method

BioPro+ has established a proprietary ratio required to preserve the biological integrity of the growth factor matrix.

Step 03 Molecular Sorting

Biologically active growth factors and peptides are isolated — those capable of binding to cellular receptors — while inactive compounds are removed.

Why It Works

The system is
why this works.

A growth factor peptide that can’t reach your cells is no growth factor at all. BioPro+® uses sublingual delivery — held under the tongue for 90 seconds, the formula absorbs directly through the mucosal membrane, bypassing the digestive system entirely and preserving the molecular integrity of the growth factors.

The Problem Oral Degradation

Peptides swallowed in a capsule encounter stomach acid and digestive enzymes. The majority don’t survive the journey intact.

The Solution Sublingual Delivery

Held under the tongue for 90 seconds. The mucosal membrane allows peptides to enter the bloodstream directly — bypassing digestion entirely.

The Result Intact Bioavailability

Growth factors and peptides arrive at cellular receptors with their molecular integrity preserved. This is the biological reason the system works.

BioPro+® vs. Traditional Hormone Therapy
Traditional approach Traditional Hormone Therapy
Elevates hormone levels directly
Suppresses natural production
Negative endocrine feedback loop
Cycle required
Prescription needed
Synthetic hormones introduced externally. Results come at the cost of your body’s own regulatory capacity.
vs
BioPro+® approach BioPro+® Approach
Supports same downstream signaling pathways
Supports natural regulatory system
No negative feedback loop
No cycle required
No prescription needed
Bioidentical growth factor peptides. The same results — through your body’s own pathways.

Drug-free. No negative endocrine feedback loop. No prescription required. Individual results may vary.

45 Studies

The evidence, organized.

Research spanning five ingredient categories and ten health benefit domains. Studies are paraphrased for clarity — see full citations in the Executive Research Summary.

Study 41
Lycium barbarum Increases Caloric Expenditure and Decreases Waist Circumference
Plain-English explanation of how the reported findings support the selected benefit.
Two randomized controlled human trials showed Lycium barbarum increased resting metabolic rate by ~10% and reduced waist circumference by 5.5 cm in 14 days.
Study 20, 23, 29
Neuroprotective Properties of Velvet Antler Components
Plain-English explanation of how the reported findings support the selected benefit.
Components demonstrated neuroprotective activity, promoting neural stem cell growth and supporting memory and mood-regulating pathways.
Study 42
Clinical Assessment of Tribulus terrestris in Female Sexual Dysfunction
Plain-English explanation of how the reported findings support the selected benefit.
90-day RCT with 144 female subjects showed statistically significant improvement across all five domains of the Female Sexual Function Index. 88.33% response rate.
Study 2
Antler Blood Enhances Stem Cell-Derived Exosomes for Bone & Vascular Regeneration
Plain-English explanation of how the reported findings support the selected benefit.
Antler-derived blood primed exosomes to significantly enhance osteogenic differentiation and angiogenesis, accelerating bone formation and new blood vessel growth.
Study 5
Bone Metabolism Associated with Annual Antler Regeneration
Plain-English explanation of how the reported findings support the selected benefit.
Deer regenerate up to 25 kg of bone mineral within 110 days, revealing mechanisms of rapid bone turnover.
Study 7
DAV May Improve Bone Turnover and Bone Mineral Density
Plain-English explanation of how the reported findings support the selected benefit.
Velvet antler components promoted osteoblast proliferation via BMP-2, MAPK, and insulin signaling while inhibiting osteoclast-mediated bone resorption.
Study 33/36
Human RCT: Skin Hydration and Collagen Production
Plain-English explanation of how the reported findings support the selected benefit.
Randomized controlled trial demonstrated improved skin hydration and measurably increased collagen production in human subjects over the study period.
Study 1
Anti-Fatigue Peptides from Cervus elaphus Blood
Plain-English explanation of how the reported findings support the selected benefit.
Research supports the role of bioactive peptides in promoting energy metabolism, physical endurance, and healthy recovery markers.

Get the full research manual.

All 45 studies, organized by ingredient and benefit domain. The complete BioPro+ Executive Research Summary.

Download the Research Study

For research substantiation purposes only. These statements have not been evaluated by the FDA.

Physician Perspectives

What clinicians are seeing.

BioPro+® is recommended by physicians across sports medicine, functional medicine, and men’s health. The following perspectives are from practitioners who have observed BioPro+® with their patients.

Mark Gunderson
Mark Gunderson
M.D. · Age Management Institute

"BioPro+ is a fantastic alternative to HGH. I have many patients who have successfully replaced it with this product. I continuously recommend BioPro+ to my patients as a vital part of my Age Management practice."

Steven Martinez
Steven Martinez
PA-C, SSRP, IFMP · Mens Health

"I use BioPro+ personally and professionally daily. The changes I’ve seen in patients’ muscle development and fat loss are second to none."

What’s Inside

Five ingredients.
Backed by 45 studies.

Each ingredient contributes a distinct and documented mechanism. Together they address the core physiological drivers of age-related decline — declining IGF-1, bone mineral loss, reduced metabolic rate, hormonal imbalance, and impaired tissue repair.

Deer Antler Velvet Extract
30 Studies
Delivers a complete natural growth factor matrix — IGF-I, IGF-II, EGF, FGF, TGF-α/β, BMP, NGF, PDGF, VEGF — plus the full essential and non-essential amino acid spectrum, glycosaminoglycans (chondroitin sulfate, hyaluronic acid), phospholipids, and minerals. The foundational ingredient.
Bone HealthWound HealingMuscle & RecoveryHormonal SupportNeuroprotectionImmune FunctionStem Cell Science
30 Studies
Lycium Berry (Goji)
4 Studies
Human clinical research supports improvements in resting metabolic rate and body composition. Additional research documents neuroprotective, immune-supporting, and vitality-enhancing properties.
MetabolismCognitionHormonal HealthImmune Function
4 Studies
Aloe Vera
4 Studies
Controlled trials demonstrate improved skin hydration, enhanced collagen production, and accelerated wound healing. Acemannan polysaccharides support intestinal integrity and immune cell activation.
Immune FunctionSkin HealthWound HealingGut Health
4 Studies
Shilajit
3 Studies
Fulvic and humic acid content supports mitochondrial energy production, neuroprotection, and pro-cognitive activity.
CognitionBone HealthCellular Energy
3 Studies
Tribulus Extract
1 Study
"Human clinical research supports the role of key ingredients in promoting healthy hormonal balance, sexual vitality, and overall physiological function in both men and women."
Hormonal HealthSexual Vitality
1 Study
Start the Protocol

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Got Questions?

We’ve got the answers!

About BioPro+

Usage, Dosage, and Results

Safety, Interactions, and Side Effects

Storage and Reactions to Use